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Introduction to 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine,Cas: 865363-93-5

4'-Ethynyl-2-fluoro-2'-deoxyadenosine,865363-93-5 is a synthetic compound that belongs to the class of nucleoside analogues. It is a modified form of the natural nucleoside adenosine, where specific chemical modifications have been made to enhance its properties and potential applications in various fields. This article will provide an overview of 4'-Ethynyl-2-fluoro-2'-deoxyadenosine, highlighting its structure, properties, and potential applications.Structure and Properties:4'-Ethynyl-2-fluoro-2'-deoxyadenosine is derived from the nucleoside adenosine by the introduction of an ethynyl g [...]

Apr 18, 2025 Product News 456 Views Read More

Unlocking the Potential of Ent-Idoxuridine Clinical Applications

Ent-Idoxuridine, also known as 5-iodo-2'-deoxyuridine, is a cytosolic DNA synthesis inhibitor that acts by blocking the conversion of deoxycytidine to deoxyadenosine through the inhibition of the enzyme deoxycytidine kinase. As an enantiomer of idoxuridine, it shares the same mechanism of action. Notably, ent-idoxuridine is resistant to exonucleases and has demonstrated effectiveness in treating immunodeficiency caused by HIV.CAS Number and Chemical Properties:English Name: IdoxuridineEnglish Synonyms:  2'-Deoxy-L-5-iodouridine CAS Number: 162239-35-2Molecular Formula: C9H11IN2O [...]

Apr 18, 2025 Product News 553 Views Read More

Exploring the Diverse Uses of Aminopterin: From Leukemia Treatment to Cell Culture

Aminopterin,cas: 54-62-6 also known as 4-aminopteroic acid, is a synthetic derivative of pterin and a 4-amino derivative of folic acid. It is an antineoplastic drug with immunosuppressive properties, often used in chemotherapy. Aminopterin functions as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase, effectively blocking tetrahydrofolate synthesis. This leads to the depletion of nucleotide precursors and the inhibition of DNA, RNA, and protein synthesis.Discovered by Yellapragada Subbarow, Aminopterin was first used by Sidney Farber in [...]

Apr 18, 2025 Product News 595 Views Read More