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Unlocking the Potential of Ent-Idoxuridine Clinical Applications

Ent-Idoxuridine, also known as 5-iodo-2'-deoxyuridine, is a cytosolic DNA synthesis inhibitor that acts by blocking the conversion of deoxycytidine to deoxyadenosine through the inhibition of the enzyme deoxycytidine kinase. As an enantiomer of idoxuridine, it shares the same mechanism of action. Notably, ent-idoxuridine is resistant to exonucleases and has demonstrated effectiveness in treating immunodeficiency caused by HIV.CAS Number and Chemical Properties:English Name: IdoxuridineEnglish Synonyms:  2'-Deoxy-L-5-iodouridine CAS Number: 162239-35-2Molecular Formula: C9H11IN2O [...]

Oct 31, 2024 Product News 421 Views Read More

Aminopterin,CAS:54-62-6: A Promising Antifolate Agent

Introduction:Aminopterin is a pharmacological compound that belongs to the class of antifolate agents. It has gained significant attention in the field of medicine due to its potential therapeutic applications. This article aims to provide a comprehensive overview of aminopterin, including its chemical structure, mechanism of action, medical uses, and associated risks.Chemical Structure:Aminopterin, also known as 4-aminofolic acid, is a synthetic analogue of folic acid. It possesses a similar chemical structure to dihydrofolate, which is an essential component in the synthesis of nucleic acids [...]

Oct 31, 2024 Product News 353 Views Read More

Diazoxide: Understanding Its Role as a Thiazide Antihypertensive Drug

Introduction Diazoxide, also known by its chemical name 7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide, 364-98-7 is a medication with a range of applications in the field of medicine. This comprehensive guide aims to provide an in-depth understanding of diazoxide, including its uses, dosage, potential side effects, contraindications, and precautions. Whether you are a healthcare professional or an individual seeking information about this medication, this guide will serve as a valuable resource.Uses Diazoxide is primarily used to treat persistent hyperinsulinemic hypogly [...]

Oct 31, 2024 Product News 443 Views Read More