Exploring the Diverse Uses of Aminopterin: From Leukemia Treatment to Cell Culture

Aminopterin,cas: 54-62-6 also known as 4-aminopteroic acid, is a synthetic derivative of pterin and a 4-amino derivative of folic acid. It is an antineoplastic drug with immunosuppressive properties, often used in chemotherapy. Aminopterin functions as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase, effectively blocking tetrahydrofolate synthesis. This leads to the depletion of nucleotide precursors and the inhibition of DNA, RNA, and protein synthesis.Discovered by Yellapragada Subbarow, Aminopterin was first used by Sidney Farber in [...]

VERSATILE AMMONIUM SALICYLATE CAS: 528-94-9

2-Hydroxybenzoic acid ammonium salt, also known as ammonium salicylate, is an organic ammonium salt formed by the reaction of salicylic acid with ammonia or ammonium hydroxide. It exhibits excellent water solubility and differs in properties from salicylic acid. Unlike salicylic acid, ammonium salicylate does not sublime and has a certain degree of heat resistance, which prevents the decomposition and formation of phenol at high temperatures. AMMONIUM SALICYLATE CAS: 528-94-9 is Used for:Application 1: Ammonium salicylate is used in the preparation of [...]

Exploring the Versatile Applications of 2,3,3-Trimethyl-3H-indole-5-sulfonic Acid;CAS : 132557-72-3

2,3,3-Trimethyl-3H-indole-5-sulfonic acid 132557-72-3 is a chemical compound with a wide range of applications in various industries. This compound, Molecular Formula: C17H28N2O3S is a sulfonic acid derivative of indole, a heterocyclic aromatic organic compound. It has several important uses, including as a building block in the synthesis of pharmaceuticals, dyes, and other organic compounds.One of the key applications of 2,3,3-Trimethyl-3H-indole-5-sulfonic acid is in the pharmaceutical industry. It serves as a crucial intermediate in the synthesis of various pharmaceutical products. Its uniq [...]