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Unlocking the Potential of Ent-Idoxuridine Clinical Applications

Ent-Idoxuridine, also known as 5-iodo-2'-deoxyuridine, is a cytosolic DNA synthesis inhibitor that acts by blocking the conversion of deoxycytidine to deoxyadenosine through the inhibition of the enzyme deoxycytidine kinase. As an enantiomer of idoxuridine, it shares the same mechanism of action. Notably, ent-idoxuridine is resistant to exonucleases and has demonstrated effectiveness in treating immunodeficiency caused by HIV.CAS Number and Chemical Properties:English Name: IdoxuridineEnglish Synonyms:  2'-Deoxy-L-5-iodouridine CAS Number: 162239-35-2Molecular Formula: C9H11IN2O [...]

Nov 21, 2024 Product News 437 Views Read More

Understanding the Role of Quinidine in Managing Cardiac Arrhythmias

Quinidine is a medication that belongs to a class of drugs known as antiarrhythmics. It is primarily used to treat certain types of irregular heartbeats (arrhythmias) and to maintain a normal heart rhythm. This compound has a long history of use in medicine and has been an important tool in the treatment of various cardiac conditions.Quinidine works by stabilizing the heart's electrical activity, specifically by prolonging the action potential duration and refractory period of the cardiac muscle. This action helps to prevent abnormal electrical signals in the heart, thereby restoring and maint [...]

Nov 21, 2024 Product News 406 Views Read More

Aminopterin,CAS:54-62-6: A Promising Antifolate Agent

Introduction:Aminopterin is a pharmacological compound that belongs to the class of antifolate agents. It has gained significant attention in the field of medicine due to its potential therapeutic applications. This article aims to provide a comprehensive overview of aminopterin, including its chemical structure, mechanism of action, medical uses, and associated risks.Chemical Structure:Aminopterin, also known as 4-aminofolic acid, is a synthetic analogue of folic acid. It possesses a similar chemical structure to dihydrofolate, which is an essential component in the synthesis of nucleic acids [...]

Nov 20, 2024 Product News 367 Views Read More