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Exploring the Diverse Uses of Aminopterin: From Leukemia Treatment to Cell Culture

Aminopterin,cas: 54-62-6 also known as 4-aminopteroic acid, is a synthetic derivative of pterin and a 4-amino derivative of folic acid. It is an antineoplastic drug with immunosuppressive properties, often used in chemotherapy. Aminopterin functions as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase, effectively blocking tetrahydrofolate synthesis. This leads to the depletion of nucleotide precursors and the inhibition of DNA, RNA, and protein synthesis.Discovered by Yellapragada Subbarow, Aminopterin was first used by Sidney Farber in [...]

Jul 05, 2025 Product News 764 Views Read More

Linoleic Acid vs. Linolenic Acid Difference

Linoleic acid and linoleic acid cannot be synthesized in the body, or the amount synthesized is far from meeting the daily fatty acid needs, essential fatty acids.Essential fatty acids refer to polyunsaturated fatty acids (PUFA) that are essential for the body's life activities, but the body itself cannot synthesize them and must be supplied by food. There are two main types of essential fatty acids, one is α-linolenic acid (18:3) in the ω-3 series, and the other is linoleic acid (18:2) in the ω-6 series.. Linolenic acid (α-linolenic acid cas:463-40-1 and γ-linolenic acid):α-linolenic aci [...]

Jul 05, 2025 Product News 365 Views Read More

Introduction of product 9-Methoxy-9-borabicyclo[3.3.1]nonane,38050-71-4

9-Methoxy-9-borabicyclo[3.3.1]nonane,38050-71-4 commonly known as B-Methoxy-9-BBN, is a versatile and valuable reagent in organic synthesis. This compound belongs to the family of boron-organic compounds and is widely used in various chemical reactions due to its unique properties. In this article, we will explore the structure, synthesis, reactivity, and applications of 9-Methoxy-9-borabicyclo[3.3.1]nonane in organic chemistry.Structure:9-Methoxy-9-borabicyclo[3.3.1]nonane is a bicyclic compound consisting of a boron atom and a bicyclic framework. The boron atom is attach [...]

Jul 05, 2025 Product News 872 Views Read More