L-Glutamic acid, 5-(2-propen-1-yl) ester: A Versatile Building Block for Advanced Biopolymer Synthesis
Finetech Industry Limited is proud to supply high-purity L-Glutamic acid, 5-(2-propen-1-yl) ester (CAS: 145058-42-0), a specialized amino acid derivative engineered for cutting-edge research in medicinal chemistry and materials science.
Technical
Specifications
|
Property |
Data |
|
English Name |
L-Glutamic acid, 5-(2-propen-1-yl) ester |
|
Synonym |
gamma-Allyl-L-glutamate |
|
CAS Number |
145058-42-0 |
|
Molecular Formula |
C8H13NO4 |
|
Molecular Weight |
187.19 g/mol |
|
Purity |
95% |
Key Applications
in Modern Research
The presence of the allyl ester group at the gamma-position
of the L-glutamic acid backbone makes this compound a vital reagent for
researchers focusing on:
1. Polypeptide and
Hydrogel Engineering
gamma-Allyl-L-glutamate is frequently used as a
monomer in the synthesis of poly(L-glutamic acid) (PGA) derivatives. The
allyl side chain serves as a "handle" for subsequent
functionalization via Thiol-ene click chemistry, allowing for the
precise attachment of drugs, fluorophores, or cross-linking agents.
2. Biocompatible
Scaffold Development
Due to its inherent chirality and biological
relevance, this ester is a preferred starting material for creating
biodegradable polymers used in tissue engineering and Controlled-release drugs delivery systems.
3. Synthetic
Organic Chemistry
It serves as a versatile intermediate for the
synthesis of complex unnatural amino acids and peptidomimetics, often appearing
in methodologies involving Ring-Closing Metathesis (RCM).
Scholarly
Significance and Citations
The utility of CAS 145058-42-0 is well-documented in
high-impact literature. Research involving this moiety often explores the
transition from simple amino acid esters to complex macromolecular
architectures.
Academic Note: > Studies
published in journals such as Biomacromolecules and Polymer Chemistry
frequently cite the use of gamma-substituted glutamate esters to achieve
"smart" stimuli-responsive polymers. The allyl functionality is
specifically praised for its stability during polymerization and its high
reactivity during post-polymerization modification.
Why Source from
Finetech Industry Limited?
At Finetech Industry Limited, we understand
that the integrity of your research depends on the purity of your reagents.
- Analytical Consistency: Every batch
is accompanied by comprehensive COA and NMR.
- Scalability: From
milligram-scale pilot studies to bulk industrial requirements.
- Global Logistics: Efficient,
compliant shipping to academic institutions and R&D centers worldwide.
Request a Quote
Enhance your research with premium-grade L-Glutamic
acid, 5-(2-propen-1-yl) ester.
Contact our technical sales team
at Finetech Industry Limited today.