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Idarubicin: Mechanism of Action, Side Effects, and Clinical Applications in Cancer Treatment

Idarubicin 57852-57-0is a potent chemotherapy drug belonging to the anthracycline class, primarily used in the treatment of various types of cancer, including acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL). Its mechanism of action, side effects, and clinical applications make it a crucial component of cancer treatment regimens.Mechanism of Action:Idarubicin exerts its anticancer effects by interfering with the DNA and RNA synthesis of cancer cells. It does so by intercalating between DNA base pairs, inhibiting the activity of topoisomerase II enzyme, and generating free radi [...]

Jul 23, 2025 Product News 851 Views Read More

Exploring the Therapeutic Potential of Triptolide: A Natural Compound with Diverse Pharmacological Properties

Triptolide Cas:38748-32-2 is a naturally occurring diterpenoid compound derived from the Chinese herb Tripterygium wilfordii, also known as Thunder God Vine. It has been used in traditional Chinese medicine for centuries to treat a variety of inflammatory and autoimmune conditions. In recent years, Triptolide has garnered significant attention from the scientific community due to its potent anti-inflammatory, immunosuppressive, and anti-cancer properties.Research has shown that Triptolide exhibits broad-spectrum anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokin [...]

Jul 23, 2025 Product News 1502 Views Read More

Unveiling the Potential of Bardoxolone Methyl(218600-53-4): A Comprehensive Overview

Bardoxolone methyl 218600-53-4 is a synthetic triterpenoid compound that has garnered significant attention in the field of medicine due to its potential therapeutic properties. This article aims to provide an in-depth overview of bardoxolone methyl, including its mechanism of action, current and potential medical applications, as well as the latest research and clinical developments surrounding this compound.Mechanism of Action:Bardoxolone methyl exerts its pharmacological effects primarily through the activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. Nrf2 is [...]

Jul 23, 2025 Product News 570 Views Read More