Unlocking the Potential of Ent-Idoxuridine Clinical Applications
Ent-Idoxuridine, also known as 5-iodo-2'-deoxyuridine, is a cytosolic DNA synthesis inhibitor that acts by blocking the conversion of deoxycytidine to deoxyadenosine through the inhibition of the enzyme deoxycytidine kinase. As an enantiomer of idoxuridine, it shares the same mechanism of action. Notably, ent-idoxuridine is resistant to exonucleases and has demonstrated effectiveness in treating immunodeficiency caused by HIV.CAS Number and Chemical Properties:English Name: IdoxuridineEnglish Synonyms: 2'-Deoxy-L-5-iodouridine CAS Number: 162239-35-2Molecular Formula: C9H11IN2O [...]